Differences of Relationships between Iodine and Trace Elements in Normal Thyroid and Thyroid Benign Nodules Revealed by X-Ray Fluorescent Analysis

Thyroid Benign Nodules (TBN) are the most common lesions of this endocrine gland. The etiology TBN is not clear. aim exploratory study was to examine differences in content bromine (Br), cooper (Cu), iron (Fe), iodine (I), rubidium (Rb), strontium (Sr), and zinc (Zn), as well I/Br, I/Cu, I/Fe, I/Rb, I/Sr, I/Zn ratios tissues normal thyroid TBN. tissue levels seven Trace Elements (TEs) were prospectively evaluated 105 apparently healthy persons 79 patients with Measurements performed using 109Cd 241Am radionuclide-induced energy-dispersive X-ray fluorescent analysis. Tissue samples divided into two portions. One used for morphological while other intended TEs It observed that mass fraction Br, Cu, Fe higher, whereas fractions I lower than thyroid. These changes can potentially be markers. Furthermore, it found Fe, Rb, Sr, Zn contents affected gland interconnected depend on tissue. Because plays a decisive role function gland, data obtained allow us conclude that, along I, at least such Zn, if directly, then indirectly, involved process hormone synthesis.